Article
Evolutionary histories and antimicrobial resistance in Shigella flexneri and Shigella sonnei in Southeast Asia.
Communications biology - 19 Mar 2021
Chung The Hao, Bodhidatta Ladaporn, Pham Duy Thanh, Mason Carl J, Ha Thanh Tuyen, Voong Vinh Phat, Turner Paul, Hem Sopheak, Dance David A B, Newton Paul N, Phetsouvanh Rattanaphone, Davong Viengmon, Thwaites Guy E, Thomson Nicholas R, Baker Stephen, Rabaa Maia A
Abstract excerpt
Conventional disease surveillance for shigellosis in developing country settings relies on serotyping and low-resolution molecular typing, which fails to contextualise the evolutionary history of the genus. Here, we interrogated a collection of 1,804 Shigella whole genome sequences from organisms isolated in four continental Southeast Asian countries (Thailand, Vietnam, Laos, and Cambodia) over three decades to...
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