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VEXAS syndrome in myelodysplastic syndrome with autoimmune disorder

19 Mar 2021

Abstract excerpt

VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is a newly-described adult-onset inflammatory syndrome characterized by vacuoles in myeloid and erythroid precursor cells and somatic mutations affecting methionine-41 (p.Met41) in UBA1. The VEXAS syndrome often overlaps with myelodysplastic syndromes (MDS) with autoimmune disorders (AD). By screening the UBA1 gene sequences derived from...

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PMID: 33741056
DOI: 10.1186/s40164-021-00217-2

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VEXAS syndrome in myelodysplastic syndrome with autoimmune disorderPMID 33741056Read ↗

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