Article
Complement component factor B has thrombin-like activity.
Biochemical and biophysical research communications - 7 May 2021
Takahashi Kazue, Banda Nirmal K, Holers V Michael, Van Cott Elizabeth M
Abstract excerpt
Serine proteases are fundamental components of biology, including innate immunity, which is systematically orchestrated in an orderly, balanced fashion in the healthy host. Such serine proteases are found in two well-recognized pathways of an innate immune network, coagulation and complement. Both pathways, if uncontrolled due to a variety of causes, are pathogenic in numerous diseases, including coagulation...
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