Article
Relationship between PD-L1 expression and outcome in EGFR-mutant lung cancer patients treated with EGFR tyrosine kinase inhibitors.
Lung cancer (Amsterdam, Netherlands) - 1 May 2021
Liu Jia, Itchins Malinda, Nagrial Adnan, Cooper Wendy A, De Silva Madhawa, Barnet Megan, Varikatt Winny, Sivasubramaniam Vanathi, Davis Alexander, Gill Anthony J, Blinman Prunella, Lee Kenneth, Hui Rina, Gao Bo, Pavlakis Nick, Clarke Stephen, Lee Jenny, Boyer Michael, Kao Steven
Abstract excerpt
OBJECTIVES: Predictive biomarkers for poor response to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) is an area of ongoing research. This multicentre retrospective study sought to determine the impact of programmed death-ligand 1 (PD-L1) tumour proportional score (TPS) on outcome in EGFR TKI treated patients. MATERIALS AND METHODS: Patients with Stage IIIB/IV lung adenocarcinoma...
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