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Article

The efficacy of omalizumab treatment in chronic spontaneous urticaria is associated with basophil phenotypes.

The Journal of allergy and clinical immunology - 1 Jun 2021

Johal Kirti J, Chichester Kristin L, Oliver Eric T, Devine Kelly C, Bieneman Anja P, Schroeder John T, MacGlashan Donald W, Saini Sarbjit S

Abstract excerpt

BACKGROUND: The mechanisms underlying disease pathogenesis in chronic spontaneous urticaria (CSU) and improvement with omalizumab are incompletely understood. OBJECTIVES: This study sought to examine whether the rate of clinical remission is concordant with baseline basophil features or the rate of change of IgE-dependent functions of basophils and/or plasmacytoid dendritic cells during omalizumab therapy....

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Source

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Identifiers

PMID: 33713769
DOI: 10.1016/j.jaci.2021.02.038
PMCID: PMC8223444

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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