Article
Functional and phenotypic analysis of basophils allows determining distinct subtypes in patients with chronic urticaria.
Allergy - 1 Dec 2017
Rauber M M, Pickert J, Holiangu L, Möbs C, Pfützner W
Abstract excerpt
BACKGROUND: Chronic urticaria (CU) is a frequent skin disease characterized by relapsing appearance of pruritic hives. While clinical symptoms are due to the release of histamine by cutaneous mast cells, the underlying pathophysiology is still unknown. However, previous studies indicate that basophils might be of relevance. Besides, the occurrence of autoantibodies against IgE or its receptor, FcεRI, and the...
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