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A Caenorhabditis elegans behavioral assay distinguishes early stage prostate cancer patient urine from controls

8 Mar 2021

Abstract excerpt

ABSTRACT Current methods for non-invasive prostate cancer (PrCa) detection have a high false-positive rate and often result in unnecessary biopsies. Previous work has suggested that urinary volatile organic compound (VOC) biomarkers may be able to distinguish PrCa cases from benign disease. The behavior of the nematode Caenorhabditis elegans has been proposed as a tool to take advantage of these potential VOC...

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PMID: 33685856
DOI: 10.1242/bio.057398

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