Article
Identification of a novel protein in porcine astrovirus that is important for virus replication.
Veterinary microbiology - 1 Apr 2021
Du Yanjie, Ji Chengyuan, Liu Teng, Zhang Wenchao, Fang Qingli, Dong Qinting, Li Mingyang, Wang Hao, Chen Ying, Ouyang Kang, Wei Zuzhang, Huang Weijian
Abstract excerpt
Overlapping genes are common in some RNA viruses. It has been proposed that a potential overlapping gene is the ORFX, here termed ORF2b, which overlaps the ORF2 coding sequence in astroviruses. The aim of this study was to determine whether ORF2b is an overlapping gene that encodes a functional protein which is needed for viral replication. Sequence alignment showed that there was an ORF2b in a PAstV type 1...
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