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Article

Variation in VKORC1 Is Associated with Vascular Dementia.

Journal of Alzheimer's disease : JAD - 1 Jan 2021

Mur Jure, McCartney Daniel L, Chasman Daniel I, Visscher Peter M, Muniz-Terrera Graciela, Cox Simon R, Russ Tom C, Marioni Riccardo E

Abstract excerpt

BACKGROUND: The genetic variant rs9923231 (VKORC1) is associated with differences in the coagulation of blood and consequentially with sensitivity to the drug warfarin. Variation in VKORC1 has been linked in a gene-based test to dementia/Alzheimer's disease in the parents of participants, with suggestive evidence for an association for rs9923231 (p = 1.8×10-7), which was included in the genome-wide significant...

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Identifiers

PMID: 33682710
DOI: 10.3233/JAD-201256
PMCID: PMC8150662

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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