Article
Knockdown of E-cadherin induces cancer stem-cell-like phenotype and drug resistance in cervical cancer cells.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Oct 2021
Sharma Anuka, Kaur Harmandeep, De Renaissa, Srinivasan Radhika, Pal Arnab, Bhattacharyya Shalmoli
Abstract excerpt
Cervical cancer is one of the leading causes of mortality amongst women in developing countries, and resistance to therapy is the main reason for treatment failure. Recent advances suggest that cancer stem cells (CSCs) are critically involved in regulating the chemo-resistant behavior of cervical cancer cells. In our study, cells with the CSC phenotype were isolated, and we examined the expression levels of stem...
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