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Article

First trimester mechanisms of gestational sac placental and foetal teratogenicity: a framework for birth cohort studies

29 Dec 2020

Abstract excerpt

BACKGROUND: The function of the gestational sac (GS) and the placenta in the closely related processes of embryogenesis and teratogenicity in the first trimester has been minimally described. The prevailing assumption is that direct teratogenic effects are mediated by the critical extraembryonic organ, the placenta, which either blocks or transfers exposures to the foetus. Placental transfer is a dominant...

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PMID: 33675653
DOI: 10.1093/humupd/dmaa063

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