Specified critical period of different congenital abnormalities: A new approach for human teratological studies

Abstract excerpt

The first trimester has been evaluated at different exposures as the critical period of congenital abnormalities. However, the first trimester concept has no scientific basis because environmental agents (teratogens) cannot induce congenital abnormalities during the first gestational month calculated from the first day of the last menstrual period. In addition, the critical period of some congenital...

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