Article
Molecular Alterations in Pancreatic Cancer: Transfer to the Clinic.
International journal of molecular sciences - 19 Feb 2021
Rodríguez Gil Yolanda, Jiménez Sánchez Paula, Muñoz Velasco Raúl, García García Ana, Sánchez-Arévalo Lobo Víctor Javier
Abstract excerpt
Pancreatic ductal adenocarcinoma (PDA) is the most common cancer of the exocrine pancreas and probably the tumor that has benefited the least from clinical progress in the last three decades. A consensus has been reached regarding the histologic classification of the ductal preneoplastic lesions (pancreatic intra-epithelial neoplasia-PanIN) and the molecular alterations associated with them. Mutations in KRAS and...
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