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Article

The Role of Mitochondria in the Chemoresistance of Pancreatic Cancer Cells

25 Feb 2021

Abstract excerpt

The first-line chemotherapies for patients with unresectable pancreatic cancer (PC) are 5-fluorouracil (5-FU) and gemcitabine therapy. However, due to chemoresistance the prognosis of patients with PC has not been significantly improved. Mitochondria are essential organelles in eukaryotes that evolved from aerobic bacteria. In recent years, many studies have shown that mitochondria play important roles in...

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PMID: 33669111
DOI: 10.3390/cells10030497

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