Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neurodevelopmental and transcriptomic effects of CRISPR/Cas9-induced somatic orco mutation in honey bees.

Journal of neurogenetics - 1 Sept 2021

Chen Zhenqing, Traniello Ian M, Rana Seema, Cash-Ahmed Amy C, Sankey Alison L, Yang Che, Robinson Gene E

Abstract excerpt

In insects, odorant receptors facilitate olfactory communication and require the functionality of the highly conserved co-receptor gene orco. Genome editing studies in a few species of ants and moths have revealed that orco can also have a neurodevelopmental function, in addition to its canonical role in adult olfaction, discovered first in Drosophila melanogaster. To extend this analysis, we determined whether...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bees
Share to Brain
Share to Clustered Regularly Interspaced Short Palindromic Repeats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Genetic Engineering

Share to Mutation

Share to Neurogenesis

Share to Receptors, Odorant

Source

Identifiers

PMID: 33666542
DOI: 10.1080/01677063.2021.1887173

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neurodevelopmental and transcriptomic effects of CRISPR/Cas9-induced somatic orco mutation in honey bees.PMID 33666542Read ↗

Olfactory receptors are required for social behavior and neural plasticity in ants, as evidenced by CRISPR-mediated gene knockoutSemantic proximity Read ↗

An Engineered orco Mutation Produces Aberrant Social Behavior and Defective Neural Development in Ants.Semantic proximity Read ↗

Heritable genome editing with CRISPR/Cas9 induces anosmia in a crop pest moth.Semantic proximity Read ↗

orco Mutagenesis Causes Loss of Antennal Lobe Glomeruli and Impaired Social Behavior in Ants.Semantic proximity Read ↗

Fertility decline in female mosquitoes is regulated by the orco olfactory co-receptorSemantic proximity Read ↗

Orco-dependent survival of odorant receptor neurons in ants.Semantic proximity Read ↗

Fertility decline in female mosquitoes is regulated by the <i>orco</i> olfactory co-receptorSemantic proximity Read ↗

Production of Knockout Mutants by CRISPR/Cas9 in the European Honeybee, Apis mellifera L.Semantic proximity Read ↗

Mutagenesis of the Orco Odorant Receptor Co-receptor Impairs Olfactory Function in the Malaria Vector <i>Anopheles coluzzii</i>Semantic proximity Read ↗

The sense of smell: genomics of vertebrate odorant receptors.Semantic proximity Read ↗

An expanded neurogenetic toolkit to decode olfaction in the African malaria mosquito Anopheles gambiaeSemantic proximity Read ↗

Amplification of Olfactory Signals by Anoctamin 9 is Essential for Mammalian Olfaction: a Risk Factor for the Covid-19-associated AnosmiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.