Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heritable genome editing with CRISPR/Cas9 induces anosmia in a crop pest moth.

Scientific reports - 12 Jul 2016

Koutroumpa Fotini A, Monsempes Christelle, François Marie-Christine, de Cian Anne, Royer Corinne, Concordet Jean-Paul, Jacquin-Joly Emmanuelle

Abstract excerpt

Lepidoptera suffer critical lack of genetic tools and heritable genome edition has been achieved only in a few model species. Here we demonstrate that the CRISPR/Cas9 system is highly efficient for genome editing in a non-model crop pest Lepidoptera, the noctuid moth Spodoptera littoralis. We knocked-out the olfactory receptor co-receptor Orco gene to investigate its function in Lepidoptera olfaction. We find...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clustered Regularly Interspaced Short Palindromic Repeats
Share to CRISPR-Cas Systems

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Editing

Share to Insect Proteins

Share to Olfaction Disorders

Share to Receptors, Odorant

Share to Sex Attractants

Share to Spodoptera

Source

Open in PubMed Open full text

Identifiers

PMID: 27403935
DOI: 10.1038/srep29620
PMCID: PMC4940732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heritable genome editing with CRISPR/Cas9 induces anosmia in a crop pest moth.PMID 27403935Read ↗

Neurodevelopmental and transcriptomic effects of CRISPR/Cas9-induced somatic orco mutation in honey bees.Semantic proximity Read ↗

SeBLOS2 knockout via CRISPR/Cas9 leads to the loss of larval integument coloration in Spodoptera exigua (Lepidoptera: Noctuidae).Semantic proximity Read ↗

Functional characterization of SlitPBP3 in Spodoptera litura by CRISPR/Cas9 mediated genome editing.Semantic proximity Read ↗

CRISPR-based diagnostics detects invasive insect pestsSemantic proximity Read ↗

Olfactory receptors are required for social behavior and neural plasticity in ants, as evidenced by CRISPR-mediated gene knockoutSemantic proximity Read ↗

Mutagenesis of the Orco Odorant Receptor Co-receptor Impairs Olfactory Function in the Malaria Vector <i>Anopheles coluzzii</i>Semantic proximity Read ↗

Disruption of the odorant coreceptor Orco impairs foraging and host finding behaviors in the New World screwworm fly.Semantic proximity Read ↗

Co-CRISPR: A valuable toolkit for mutation enrichment in the gene editing of Spodoptera frugiperda.Semantic proximity Read ↗

CRISPR/Cas9-mediated PBP1 and PBP3 mutagenesis induced significant reduction in electrophysiological response to sex pheromones in male Chilo suppressalis.Semantic proximity Read ↗

A neurogenetic toolkit to decode <i>Anopheles gambiae</i> olfactionSemantic proximity Read ↗

An Engineered orco Mutation Produces Aberrant Social Behavior and Defective Neural Development in Ants.Semantic proximity Read ↗

CRISPR-Cas9 genome editing in <i>Steinernema</i> entomopathogenic nematodesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.