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Article

The utility of PRAME immunohistochemistry in the evaluation of challenging melanocytic tumors.

Journal of cutaneous pathology - 1 Sept 2021

Alomari Ahmed K, Tharp Andrew W, Umphress Brandon, Kowal Rachel P

Abstract excerpt

BACKGROUND: PRAME (PReferentially expressed Antigen in Melanoma) immunohistochemistry has demonstrated high specificity for unequivocal melanomas; however, its utility in ambiguous melanocytic neoplasms has yet to be fully elucidated. METHODS: Cases of challenging melanocytic neoplasms were subclassified into one of three categories: challenging, favor benign (FB), challenging, cannot be subclassified (CCS), or...

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Share to Antigens, Neoplasm
Share to Diagnosis, Differential

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

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Share to Melanoma, Cutaneous Malignant

Share to Sensitivity and Specificity

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Source

Identifiers

PMID: 33660310
DOI: 10.1111/cup.14000

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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