Article
The genetic background and vitamin D supplementation can affect irisin levels in Prader-Willi syndrome.
Journal of endocrinological investigation - 1 Oct 2021
Faienza M F, Brunetti G, Grugni G, Fintini D, Convertino A, Pignataro P, Crinò A, Colucci S, Grano M
Abstract excerpt
BACKGROUND: Prader-Willi syndrome (PWS) is associated to distinctive clinical symptoms, including obesity, cognitive and behavioral disorders, and bone impairment. Irisin is a myokine that acts on several target organs including brain adipose tissue and bone. The present study was finalized to explore circulating levels of irisin in children and adult PWS patients. METHODS: Seventy-eight subjects with PWS, 26...
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