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Integrative lncRNA–mRNA co‐expression network analysis identifies novel lncRNA E2F3‐IT1 for rheumatoid arthritis

1 Feb 2021

Abstract excerpt

Our previous study has reported that DNA methylation serves as an important epigenetic factor of gene–environment interaction, which contributes to pathogenesis of rheumatoid arthritis (RA).1 To investigate the role of another epigenetic factor (long noncoding RNA, lncRNA) in RA pathogenesis, we integrated lncRNA and mRNA transcriptomic information, constructed lncRNA→mRNA→RA regulatory network by performing...

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PMID: 33634971
DOI: 10.1002/ctm2.325

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