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Functional analysis of a chaetoglobosin A biosynthetic regulator in Chaetomium globosum

27 Nov 2020

Abstract excerpt

Cytochalasins are a group of fungal secondary metabolites with diverse structures and bioactivities, including chaetoglobosin A production. Chaetoglobosin A is produced by Chaetomium globosum and has potential antifungal activity. Bioinformatics analysis of the chaetoglobosin A gene cluster (che) showed it that consists of nine open reading frames, including those encoding polyketide synthases (PKSs), PKS...

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PMID: 33622536
DOI: 10.1016/j.funbio.2020.10.010

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