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Single-cell RNA sequencing reveals developmental heterogeneity among Plasmodium berghei sporozoites

22 Feb 2021

Abstract excerpt

In the malaria-causing parasite's life cycle, Plasmodium sporozoites must travel from the midgut of a mosquito to the salivary glands before they can infect a mammalian host. However, only a fraction of sporozoites complete the journey. Since salivary gland invasion is required for transmission of sporozoites, insights at the molecular level can contribute to strategies for malaria prevention. Recent advances in...

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PMID: 33619283
DOI: 10.1038/s41598-021-82914-w

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