Article
Loss-of-function HSD17B13 variants, non-alcoholic steatohepatitis and adverse liver outcomes: Results from a multi-ethnic Asian cohort.
Clinical and molecular hepatology - 1 Jul 2021
Ting Yi-Wen, Kong Amanda Shen-Yee, Zain Shamsul Mohd, Chan Wah-Kheong, Tan Hwa-Li, Mohamed Zahurin, Pung Yuh-Fen, Mohamed Rosmawati
Abstract excerpt
BACKGROUND/AIMS: 17β-hydroxysteroid dehydrogenase 13 (HSD17B13) variants were recently reported to have significantly lower odds of non-alcoholic fatty liver disease (NAFLD). This is a two-part study that aimed to evaluate the association of HSD17B13 variants with NAFLD and its histological severity, and to identify the association of the variants with clinical outcomes in a cohort of biopsy-proven NAFLD...
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