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Article

Impact of modular mitochondrial epistatic interactions on the evolution of human subpopulations.

Mitochondrion - 1 May 2021

Shinde Pramod, Whitwell Harry J, Verma Rahul Kumar, Ivanchenko Mikhail, Zaikin Alexey, Jalan Sarika

Abstract excerpt

Investigation of human mitochondrial (mt) genome variation has been shown to provide insights to the human history and natural selection. By analyzing 24,167 human mt-genome samples, collected for five continents, we have developed a co-mutation network model to investigate characteristic human evolutionary patterns. The analysis highlighted richer co-mutating regions of the mt-genome, suggesting the presence of...

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PMID: 33618020
DOI: 10.1016/j.mito.2021.02.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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