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Article

The mutation of SPI51, a protease inhibitor of silkworm, resulted in the change of antifungal activity during domestication.

International journal of biological macromolecules - 1 May 2021

Zhang Xiaolu, Ni Yuhui, Guo Kaiyu, Dong Zhaoming, Chen Yuqing, Zhu Hongtao, Xia Qingyou, Zhao Ping

Abstract excerpt

Domestication of silkworm has led to alterations in various gene expression patterns. For instance, many protease inhibitors were significantly downregulated in the domestic silkworm cocoon compared to its wild progenitor. Considering that SPI51 is the most abundant protease inhibitor in silkworm cocoons, herein, we compared the gene structures and sequences of SPI51 from B. mori (BmoSPI51) and B. mandarina...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33609582
DOI: 10.1016/j.ijbiomac.2021.02.076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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