Article
Genome-wide association studies identify two novel loci conferring susceptibility to diabetic retinopathy in Japanese patients with type 2 diabetes.
Human molecular genetics - 17 May 2021
Imamura Minako, Takahashi Atsushi, Matsunami Masatoshi, Horikoshi Momoko, Iwata Minoru, Araki Shin-Ichi, Toyoda Masao, Susarla Gayatri, Ahn Jeeyun, Park Kyu Hyung, Kong Jinhwa, Moon Sanghoon, Sobrin Lucia, Yamauchi Toshimasa, Tobe Kazuyuki, Maegawa Hiroshi, Kadowaki Takashi, Maeda Shiro
Abstract excerpt
Several reports have suggested that genetic susceptibility contributes to the development and progression of diabetic retinopathy. We aimed to identify genetic loci that confer susceptibility to diabetic retinopathy in Japanese patients with type 2 diabetes. We analysed 5 790 508 single nucleotide polymorphisms (SNPs) in 8880 Japanese patients with type 2 diabetes, 4839 retinopathy cases and 4041 controls, as...
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