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Article

Genetics of recurrent pregnancy loss: a review

16 Feb 2021

Abstract excerpt

PURPOSE OF REVIEW: Human reproduction is remarkably inefficient; with pregnancy loss occurring in 10-30% of clinically recognized pregnancies. Of those, 3-5% of couples experience recurrent pregnancy loss (RPL), more than 50% of who never receive an underlying diagnosis. Herein, we review evidence that genetic changes, including pathogenic variant(s) in highly penetrant genes, may provide an explanation for a...

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Share to Genomic variations and chromosomal abnormalities
Share to Prenatal Screening and Diagnostics
Share to Reproductive System and Pregnancy

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PMID: 33605623
DOI: 10.1097/gco.0000000000000695

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