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Article

A Saccharomyces cerevisiae model reveals in vivo functional impairment of the Ogden syndrome N-terminal acetyltransferase NAA10 Ser37Pro mutant.

Molecular & cellular proteomics : MCP - 1 Aug 2014

Van Damme Petra, Støve Svein I, Glomnes Nina, Gevaert Kris, Arnesen Thomas

Abstract excerpt

N-terminal acetylation (Nt-acetylation) occurs on the majority of eukaryotic proteins and is catalyzed by N-terminal acetyltransferases (NATs). Nt-acetylation is increasingly recognized as a vital modification with functional implications ranging from protein degradation to protein localization. Although early genetic studies in yeast demonstrated that NAT-deletion strains displayed a variety of phenotypes, only...

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Identifiers

PMID: 24408909
DOI: 10.1074/mcp.M113.035402
PMCID: PMC4125735

Genes

NAA10

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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