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Article

Development of a program for in silico optimized selection of oligonucleotide-based molecular barcodes.

PloS one - 1 Jan 2021

Yang In Seok, Bae Sang Won, Park BeumJin, Kim Sangwoo

Abstract excerpt

Short DNA oligonucleotides (~4 mer) have been used to index samples from different sources, such as in multiplex sequencing. Presently, longer oligonucleotides (8-12 mer) are being used as molecular barcodes with which to distinguish among raw DNA molecules in many high-tech sequence analyses, including low-frequent mutation detection, quantitative transcriptome analysis, and single-cell sequencing. Despite some...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33600481
DOI: 10.1371/journal.pone.0246354
PMCID: PMC7891705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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