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Article

Genetic loci associated with skin pigmentation in African Americans and their effects on vitamin D deficiency.

PLoS genetics - 1 Feb 2021

Batai Ken, Cui Zuxi, Arora Amit, Shah-Williams Ebony, Hernandez Wenndy, Ruden Maria, Hollowell Courtney M P, Hooker Stanley E, Bathina Madhavi, Murphy Adam B, Bonilla Carolina, Kittles Rick A

Abstract excerpt

A recent genome-wide association study (GWAS) in African descent populations identified novel loci associated with skin pigmentation. However, how genomic variations affect skin pigmentation and how these skin pigmentation gene variants affect serum 25(OH) vitamin D variation has not been explored in African Americans (AAs). In order to further understand genetic factors that affect human skin pigmentation and...

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PMID: 33600456
DOI: 10.1371/journal.pgen.1009319
PMCID: PMC7891745

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