Article
From chemoproteomic-detected amino acids to genomic coordinates: insights into precise multi-omic data integration.
Molecular systems biology - 1 Feb 2021
Palafox Maria F, Desai Heta S, Arboleda Valerie A, Backus Keriann M
Abstract excerpt
The integration of proteomic, transcriptomic, and genetic variant annotation data will improve our understanding of genotype-phenotype associations. Due, in part, to challenges associated with accurate inter-database mapping, such multi-omic studies have not extended to chemoproteomics, a method that measures the intrinsic reactivity and potential "druggability" of nucleophilic amino acid side chains. Here, we...
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