Article
Association between sex hormones regulation-related SNP rs12233719 and lung cancer risk among never-smoking Chinese women.
Cancer medicine - 1 Mar 2021
Qian Ying, Xie Li, Li Lei, Feng Tienan, Zhu Tengteng, Wang Ruoyang, Yang Yuqing, Zhou Baosen, Yu Herbert, Qian Biyun
Abstract excerpt
BACKGROUND: The mechanism of rapidly increased non-small cell lung cancer (NSCLC) among never-smoking Chinese women has not been elucidated. Ovarian sex steroid hormones have been suggested to counteract lung cancer development, and sex hormone-binding globulin (SHBG) is essential in sex hormones regulation. This study aims to exploring single nucleotide polymorphisms (SNPs) in genomic regions associated with...
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