Article
The role of Sfrp and DKK proteins in cardiomyocyte development.
Physiological reports - 1 Feb 2021
Hsueh Ying-Chang, Hodgkinson Conrad P, Gomez Jose A
Abstract excerpt
In this review, we summarize the role of Wnt proteins in cardiomyogenesis. More specifically, we focus on how the development of cardiomyocytes from precursor cells involves a complex interplay between Wnt canonical β-catenin signaling pathways and Wnt noncanonical signaling pathways involving PCP and JNK. We also describe recent literature which suggests that endogenous Wnt inhibitors such as the Sfrp and DKK...
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