Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The CapZ interacting protein Rcsd1 is required for cardiogenesis downstream of Wnt11a in Xenopus laevis.

Developmental biology - 1 Apr 2017

Hempel Annemarie, Kühl Susanne J, Rothe Melanie, Rao Tata Purushothama, Sirbu Ioan Ovidiu, Vainio Seppo J, Kühl Michael

Abstract excerpt

Wnt proteins are critical for embryonic cardiogenesis and cardiomyogenesis by regulating different intracellular signalling pathways. Whereas canonical Wnt/β-catenin signalling is required for mesoderm induction and proliferation of cardiac progenitor cells, β-catenin independent, non-canonical Wnt signalling regulates cardiac specification and terminal differentiation. Although the diverse cardiac malformations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Xenopus Proteins
Share to Cytoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryonic Development

Share to Myocardium

Share to NIH 3T3 Cells

Share to Organogenesis

Share to Wnt Proteins

Share to Xenopus laevis

Source

Identifiers

PMID: 28237811
DOI: 10.1016/j.ydbio.2017.02.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The CapZ interacting protein Rcsd1 is required for cardiogenesis downstream of Wnt11a in Xenopus laevis.PMID 28237811Read ↗

The Multiple Phases and Faces of Wnt Signaling During Cardiac Differentiation and DevelopmentSemantic proximity Read ↗

Myocardial Smad4 Is Essential for Cardiogenesis in Mouse EmbryosSemantic proximity Read ↗

Wnt5a Is Required for Cardiac Outflow Tract Septation in MiceSemantic proximity Read ↗

Tissue specific requirements for WNT11 in developing outflow tract and dorsal mesenchymal protrusion.Semantic proximity Read ↗

DiGeorge Syndrome Gene tbx1 Functions through wnt11r to Regulate Heart Looping and DifferentiationSemantic proximity Read ↗

A critical role for the chromatin remodeller CHD7 in anterior mesoderm during cardiovascular developmentSemantic proximity Read ↗

Congenital heart disease protein 5 associates with CASZ1 to maintain myocardial tissue integrity.Semantic proximity Read ↗

Cfdp1 Is Essential for Cardiac Development and Function.Semantic proximity Read ↗

Reduced dosage of β-catenin provides significant rescue of cardiac outflow tract anomalies in a Tbx1 conditional null mouse model of 22q11.2 deletion syndromeSemantic proximity Read ↗

The role of Sfrp and DKK proteins in cardiomyocyte development.Semantic proximity Read ↗

Prdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryo.Semantic proximity Read ↗

The transcription factor Foxc1a in zebrafish directly regulates expression of nkx2.5, encoding a transcriptional regulator of cardiac progenitor cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.