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Article

Role of Endothelial and Mesenchymal Cell Transitions in Heart Failure and Recovery Thereafter

15 Jan 2021

Abstract excerpt

Background: Mechanisms of myocardial recovery are not well elucidated. Methods: 3-month-old C57/BL6 mice were treated with Angiotensin-II infusion and N (w)-nitro-L-arginine methyl ester in drinking water to induce HF at 5 weeks. These agents were discontinued, and animals studied with echocardiographic, histological and genetic assessment every 2 weeks until week 19. mRNA was extracted from these samples and...

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PMID: 33584806
DOI: 10.3389/fgene.2020.609262

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