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Article

Role of inflammatory cytokines in genesis and treatment of atherosclerosis.

Trends in cardiovascular medicine - 1 Apr 2022

Biros Erik, Reznik Jacqueline E, Moran Corey S

Abstract excerpt

Atherosclerosis demonstrates an increased rate of vascular smooth muscle cells (VSMC) plasticity characterized by switching from the differentiated contractile phenotype to a de-differentiated synthetic state. In healthy blood vessels, phenotypic switching represents a fundamental property of VSMC in maintaining vascular homeostasis. However, in atherosclerosis, it is an initial and necessary step in VSMC-derived...

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PMID: 33571665
DOI: 10.1016/j.tcm.2021.02.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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