Article
Biomarkers in Huntington's and Parkinson's Disease.
Annals of the New York Academy of Sciences - 1 Oct 2009
O'Keeffe Gráinne C, Michell Andrew W, Barker Roger A
Abstract excerpt
Parkinson's (PD) and Huntington's disease (HD) are chronic neurodegenerative conditions of the brain with a variety of clinical presentations including a disorder of movement and a range of nonmotor deficits. HD is genetic in origin and the causative gene and protein known, namely mutant Huntingtin, which leads to widespread early neuronal dysfunction and death throughout the brain. In contrast, the etiology of...
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