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Mechanisms of DEET gustation in Drosophila.

Insect biochemistry and molecular biology - 1 Apr 2021

Shrestha Bhanu, Lee Youngseok

Abstract excerpt

DEET is the most widely used active ingredient in insect repellents and offers protection against insect bites. We previously reported that DEET suppresses the feeding behavior of Drosophila, which is guided by gustatory receptors (GRs) in bitter-sensing gustatory receptor neurons. Here, we sought to identify new candidates using egg-laying assays. Upon screening all GR mutants, GR89a was identified as a...

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PMID: 33549816
DOI: 10.1016/j.ibmb.2021.103550

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