Article
Gustatory Receptors Required for Avoiding the Toxic Compound Coumarin in Drosophila melanogaster.
Molecules and cells - 30 Apr 2016
Poudel Seeta, Lee Youngseok
Abstract excerpt
Coumarin is a phenolic compound that mainly affects the liver due to its metabolization into a toxic compound. The deterrent and ovicidal activities of coumarin in insect models such as Drosophila melanogaster have been reported. Here we explore the molecular mechanisms by which these insects protect themselves and their eggs from this toxic plant metabolite. Coumarin was fatal to the flies in a dosage-dependent...
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