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Article

Insect odorant receptors are molecular targets of the insect repellent DEET.

Science (New York, N.Y.) - 28 Mar 2008

Ditzen Mathias, Pellegrino Maurizio, Vosshall Leslie B

Abstract excerpt

DEET (N,N-diethyl-meta-toluamide) is the world's most widely used topical insect repellent, with broad effectiveness against most insects. Its mechanism of action and molecular target remain unknown. Here, we show that DEET blocks electrophysiological responses of olfactory sensory neurons to att...

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PMID: 18339904
DOI: 10.1126/science.1153121

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18339904-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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