Article
Post-transplant lymphoproliferative disorders: molecular basis of disease histogenesis and pathogenesis.
Hematological oncology - 1 Jun 2005
Capello Daniela, Rossi Davide, Gaidano Gianluca
Abstract excerpt
Post-transplant lymphoproliferative disorders (PTLD) represent a serious complication of solid organ and allogeneic bone marrow transplantation. PTLD generally display B-cell lineage derivation, involvement of extranodal sites, aggressive histology and clinical behaviour, and frequent association with EBV infection. The occurrence of IgV mutations in the overwhelming majority of PTLD documents that malignant...
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