Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Helicobacter pylori-induced gastric cancer is orchestrated by MRCKβ-mediated Siah2 phosphorylation

3 Feb 2021

Abstract excerpt

Abstract Background Helicobacter pylori-mediated gastric carcinogenesis is initiated by a plethora of signaling events in the infected gastric epithelial cells (GECs). The E3 ubiquitin ligase seven in absentia homolog 2 (Siah2) is induced in GECs in response to H. pylori infection. Posttranslational modifications of Siah2 orchestrate its function as well as stability. The aim of this study was to evaluate Siah2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Helicobacter pylori-related gastroenterology studies
Share to NF-κB Signaling Pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33536006
DOI: 10.1186/s12929-021-00710-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Helicobacter pylori-induced gastric cancer is orchestrated by MRCKβ-mediated Siah2 phosphorylationPMID 33536006Read ↗

ETS2 and Twist1 promote invasiveness of <i>Helicobacter pylori</i>-infected gastric cancer cells by inducing Siah2Semantic proximity Read ↗

Helicobacter pylori regulates stomach diseases by activating cell pathways and DNA methylation of host cellsSemantic proximity Read ↗

Molecular Signaling in Tumorigenesis of Gastric CancerSemantic proximity Read ↗

Effects of Helicobacter pylori on the expression of the FTO gene and its biological role in gastric cancerSemantic proximity Read ↗

miR-196a-5p Correlates with Chronic Atrophic Gastritis Progression to Gastric Cancer and Induces Malignant Biological Behaviors of Gastric Cancer Cells by Targeting ACER2Semantic proximity Read ↗

Evaluation of gene expression of PLEKHS1, AADAC, and CDKN3 as novel genomic markers in gastric carcinomaSemantic proximity Read ↗

Helicobacter pylori and epithelial mesenchymal transition in human gastric cancers: An update of the literatureSemantic proximity Read ↗

From inflammation to gastric cancer – the importance of Hedgehog/GLI signaling in Helicobacter pylori-induced chronic inflammatory and neoplastic diseasesSemantic proximity Read ↗

Sensitivity towards HDAC inhibition is associated with RTK/MAPK pathway activation in gastric cancer.Semantic proximity Read ↗

Remodeling of the gastric environment in Helicobacter pylori -induced atrophic gastritisSemantic proximity Read ↗

Hedgehog Signaling Links Chronic Inflammation to Gastric Cancer Precursor LesionsSemantic proximity Read ↗

Caudal type homeoboxes as a driving force in Helicobacter pylori infection-induced gastric intestinal metaplasiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.