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PROTACs: Promising Approaches for Epigenetic Strategies to Overcome Drug Resistance

4 Feb 2021

Abstract excerpt

Epigenetic modulation of gene expression is essential for tissue-specific development and maintenance in mammalian cells. Disruption of epigenetic processes, and the subsequent alteration of gene functions, can result in inappropriate activation or inhibition of various cellular signaling pathways, leading to cancer. Recent advancements in the understanding of the role of epigenetics in cancer initiation and...

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PMID: 33535953
DOI: 10.2174/1568009621666210203110857

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