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A comparative study of PCS and PAM50 prostate cancer classification schemes

2 Feb 2021

Abstract excerpt

BACKGROUND: Two prostate cancer (PC) classification methods based on transcriptome profiles, a de novo method referred to as the "Prostate Cancer Classification System" (PCS) and a variation of the established PAM50 breast cancer algorithm, were recently proposed. Both studies concluded that most human PC can be assigned to one of three tumor subtypes, two categorized as luminal and one as basal, suggesting the...

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PMID: 33531653
DOI: 10.1038/s41391-021-00325-4

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