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Spontaneous Emergence of Azithromycin Resistance in Independent Lineages of Salmonella Typhi in Northern India.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Mar 2021

Carey Megan E, Jain Ruby, Yousuf Mohammad, Maes Mailis, Dyson Zoe A, Thu Trang Nguyen Hoang, Nguyen Thi Nguyen To, Ho Ngoc Dan Thanh, Nhu Pham Nguyen Quynh, Mahindroo Jaspreet, Thanh Pham Duy, Sandha Kawaljeet Singh, Baker Stephen, Taneja Neelam

Abstract excerpt

BACKGROUND: The emergence and spread of antimicrobial resistance (AMR) pose a major threat to the effective treatment and control of typhoid fever. The ongoing outbreak of extensively drug-resistant Salmonella Typhi (S. Typhi) in Pakistan has left azithromycin as the only remaining broadly efficacious oral antimicrobial for typhoid in South Asia. Ominously, azithromycin-resistant S. Typhi organisms have been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33515460
DOI: 10.1093/cid/ciaa1773
PMCID: PMC7935384

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