Article
Different SARS-CoV-2 haplotypes associate with geographic origin and case fatality rates of COVID-19 patients.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2021
Goyal Manisha, De Bruyne Katrien, van Belkum Alex, West Brian
Abstract excerpt
The current pandemic of COVID-19 is caused by the SARS-CoV-2 virus for which many variants at the Single Nucleotide Polymorphism (SNP) level have now been identified. We show here that different allelic variants among 692 SARS-CoV-2 genome sequences display a statistically significant association with geographic origin (p < 0.000001) and COVID-19 case severity (p = 0.016). Geographic variation in itself is...
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