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Article

Functional Analysis of Single Nucleotide Polymorphism in ZUFSP Protein and Implication in Pathogenesis.

The protein journal - 1 Feb 2021

Ajadi Mary B, Soremekun Opeyemi S, Adewumi Adeniyi T, Kumalo Hezekiel M, Soliman Mahmoud E S

Abstract excerpt

Researches have revealed that functional non-synonymous Single Nucleotide Polymorphism (nsSNPs) present in the Zinc-finger with UFM1-Specific Peptidase domain protein (ZUFSP) may be involved in genetic instability and carcinogenesis. For the first time, we employed in-silico approach using predictive tools to identify and validate potential nsSNPs that could be pathogenic. Our result revealed that 8 nsSNPs (rs...

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Identifiers

PMID: 33512633
DOI: 10.1007/s10930-021-09962-z

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