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Article

Minor allele of GJA1 gene polymorphism is associated with higher heart rate during atrial fibrillation.

Scientific reports - 28 Jan 2021

Okamura Sho, Onohara Yuko, Ochi Hidenori, Tokuyama Takehito, Hironobe Naoya, Okubo Yosaku, Ikeuchi Yoshihiro, Miyauchi Shunsuke, Chayama Kazuaki, Kihara Yasuki, Nakano Yukiko

Abstract excerpt

Atrial fibrillation (AF) tachycardia causes heart failure and requires more attention. The genetic background of individual heart rate (HR) variations during AF are unclear. We hypothesized that HR-associated single nucleotide polymorphisms (SNPs) reported in Genome-Wide Association Studies (GWAS) are also associated with HR during AF. We enrolled patients with persistent AF (311 for screening and 146 for...

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Identifiers

PMID: 33510344
DOI: 10.1038/s41598-021-82117-3
PMCID: PMC7844413

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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