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Article

Tumor Tissue- versus Plasma-based Genotyping for Selection of Matched Therapy and Impact on Clinical Outcomes in Patients with Metastatic Breast Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jun 2021

Vidula Neelima, Niemierko Andrzej, Malvarosa Giuliana, Yuen Megan, Lennerz Jochen, Iafrate A John, Wander Seth A, Spring Laura, Juric Dejan, Isakoff Steven, Younger Jerry, Moy Beverly, Ellisen Leif W, Bardia Aditya

Abstract excerpt

PURPOSE: Actionable mutations can guide genotype-directed matched therapy. We evaluated the utility of tissue-based and plasma-based genotyping for the identification of actionable mutations and selection of matched therapy in patients with metastatic breast cancer (MBC). EXPERIMENTAL DESIGN: Patients with MBC who underwent tissue genotyping (institutional platform, 91-gene assay) or plasma-based cell-free DNA...

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PMID: 33504549
DOI: 10.1158/1078-0432.CCR-20-3444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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