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Article

Acceleration of Age-Associated Methylation Patterns in HIV-1-Infected Adults

25 Mar 2015

Abstract excerpt

Patients with treated HIV-1-infection experience earlier occurrence of aging-associated diseases, raising speculation that HIV-1-infection, or antiretroviral treatment, may accelerate aging. We recently described an age-related co-methylation module comprised of hundreds of CpGs; however, it is unknown whether aging and HIV-1-infection exert negative health effects through similar, or disparate, mechanisms. We...

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PMID: 25807146
DOI: 10.1371/journal.pone.0119201

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