Primary Immunodeficiency Disease Mimicking Pediatric Bechet’s Disease

Abstract excerpt

Behcet’s disease (BD) is a chronic inflammatory disease with multisystemic involvement. Its etiology is considered to involve complex environmental and genetic factors. Several susceptibility genes for BD, such as human leukocyte antigen (HLA)-A26, IL23R-IL12RB2, IL10 and ERAP1, in addition to the well-studied HLA-B51, were mainly identified by genome-wide association studies. A heterozygous mutation in TNFAIP3,...

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• Inflammasome and immune disorders
• Ocular Diseases and Behçet’s Syndrome
• Otitis Media and Relapsing Polychondritis